Cox event history is a branch of statistics that deals mainly with
the death of biological organisms and the failure of mechanical systems.
It is also sometimes referred to as a statistical method for analyzing
survival data. Cox event history is also known as various other names,
such as survival analysis, duration analysis, or transition analysis.
Generally speaking, this technique involves the modeling of data
structured in a time-to-event format. The goal of this analysis is to
understand the probability of the occurrence of an event. Cox event
history was primarily developed for use in medical and biological
sciences. However, this technique is now frequently used in engineering
as well as in
statistical and data analysis.
One
of the key purposes of the Cox event history technique is to explain
the causes behind the differences or similarities between the events
encountered by subjects. For instance, Cox regression may be used to
evaluate why certain individuals are at a higher risk of contracting
some diseases. Thus, it can be effectively applied to studying acute or
chronic diseases, hence the interest in Cox regression by the medical
science field. The Cox event history model mainly focuses on the hazard
function, which produces the probability of an event occurring randomly
at random times or at a specific period or instance in time.
The basic Cox event history model can be summarized by the following function:
h(t) = h0(t)e(b1X1 + b2X2 + K + bnXn)
Where; h(t) = rate of hazard
h0(t) = baseline hazard function
bX’s = coefficients and covariates.
Cox event history can be categorized mainly under three models: nonparametric, semi-parametric and parametric.
Non-parametric:
The non-parametric model does not make any assumptions about the hazard
function or the variables affecting it. Consequently, only a limited
number of variable types can be handled with the help of a
non-parametric model. This type of model involves the analysis of
empirical data showing changes over a period of time and cannot handle
continuous variables.
Semi-parametric: Similiar
to the non-parametric model, the semi-parametric model also does not
make any assumptions about the shape of the hazard function or the
variables affecting it. What makes this model different is that it
assumes the rate of the hazard is proportional over a period of time.
The estimates for the hazard function shape can be derived empirically
as well. Multivariate analyses are supported by semi-parametric models
and are often considered a more reliable fitting method for use in a Cox
event history analysis.
Parametric: In this
model, the shape of the hazard function and the variables affecting it
are determined in advance. Multivariate analyses of discrete and
continuous explanatory variables are supported by the parametric model.
However, if the hazard function shape is incorrectly estimated, then
there is a chance that the results could be biased. Parametric models
are frequently used to analyze the nature of time dependency. It is also
particularly useful for predictive modeling, because the shape of the
baseline hazard function can be
determined correctly by the parametric model.
Cox event history analysis involves the use of certain assumptions. As with every other
statistical method or technique,
if an assumption is violated, it will often lead to the results being
statistically unreliable. The major assumption is that in using Cox
event history, with the passage of time, independent variables do not
interact with each other. In other words, the independent variables
should have a constant hazard of rate over time.
In
addition, hazard rates are rarely smooth in reality. Frequently, these
rates need to be smoothed over in order for them to be useful for Cox
event history analysis.
Applications of Cox Event History
Cox
event history can be applied in many fields, although initially it was
used primarily in medical and other biological sciences. Today, it is an
excellent tool for other applications, frequently used as a statistical
method where the dependent variables are categorical, especially in
socio-economic analyses. For instance, in the field of economics, Cox
event history is used extensively to relate macro or micro economic
indicators in terms of a time series; for instance, one could determine
the relationship between unemployment or employment over time. In
addition, in commercial applications, Cox event history can be applied
to estimate the lifespan of a certain machine and break down points
based on historical data.
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